Bioavailabillity File: ETODOLAC

Aysel Beniz ÖLÇER*, Nursin GÖNÜL*º

*Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06100 Tandogan, Ankara, TURKEY.
**This Study is a part of Aysel Bediz-Ölçer’s Ph.D Thesis.
°Corresponding Author

Summary:
Etodolac is pyranocarboxylic acid derivative and a compound in the structure of etodolic acid. It is a new and reletively potent nonsteroidal antiinflammatory drug(NSAID) which has analgesic, antiarthritic and antiinflammatory effects.It is used in the treatment of rheumatoid arthritis, osteoartritis, ankylosing spondylitis, tendinitis, bursitis and soft tissue inflammations like tenosinovitis; acute sport injuries and postsurgical pains. In this article, the physicochemical properties, quantification methods, pharmacological, pharmacodynamic and pharmacokinetic properties, bioavailability and drug interactions of etodolac were outlined.

Key words:
Etodolac, NSAIDs, Pharmacokinetic, Bioavailability.