ANTIOXIDANT ACTIVITIES OF INDOLE AND BENZIMIDAZOLE DERIVATIVES

Sibel SÜZEN*°, Zeynep ALAGÖZ*, M.Orhan PÜSKÜLLÜ*

*Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100 Tandogan, Ankara, TURKEY.
°Corresponding Author

Summary:
There is a possible role of free radicals such as superoxide anion, hydroxyl anion and hydrogen peroxide in the etiology of important diseases such as atherosclerosis, nephritis and carcinogenesis. The antioxidants and antioxidant enzyme systems are the major protective systems of the organism. However, environmental chemicals can decrease the antioxidant level of organism and thus lead to cancer and various diseases. Hence, synthetic antioxidant compounds are required from external sources. There are a number of studies which report that indole and benzimidazole derivatives have antioxidant activity, and this plays an important role in the immune system. Herein have been reported the recent developments of the antioxidant activities of indole and benzimidazole derivatives.

Key words:
Antioxidant, Free radicals, Indole, Benzimidazole.