NMR SPECTROSCOPY
Hülya AKGÜN* °
*Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100 Ankara, TURKEY.
°Corresponding Author

Summary:
Nuclear Magnetic Resonance(NMR) spectroscopy has become a vital diagnostic tool in chemistry, biochemistry, physics, and, in recent years, medicine. Structure elucidation of organic and drug molecules and in vivo investigation of the basic building blocks of living organisms which contain ¹H, ¹³C and ³¹P elements have become and easy task after the advent of FT NMR spectroscopy. New techniques of NMR spectroscopy are being developed constantly in an effort to solve problems where NMR may have a potential and to broaden the range of applicabilitiy. In this paper, one dimensional NOE, INEPT, ¹³C, DEPT, and INADEQUATE and two dimensional J-resolved, COSY, INADEQUATE, NOESY and ³¹P techniques of NMR spectroscopy and the principles of NMR spectroscopy applications in biochemistry and medicine are reviwed.

Keywords:
NMR spectroscopy, NOE, INEPT, ¹³C, DEPT, INADEQUATE, J-resolved, COSY, NOESY, ³¹P, in vivo NMR, magnetic resonance tomography.