TECHNETHIUM
99m-DTPA
Meliha KORKMAZ*, A. Yekta ÖZER* °
*Hacettepe University, Faculty of Pharmacy, Department
of Radiopharmacy, 06100 Ankara, TURKEY.
°Corresponding Author
Summary:
Tc-99m-DTPA is a widely used agent in nuclear medicine
practice. For more than two decades it has been subjected
to many experimental and clinical studies. This molecule,
because of its suitable characteristics can also be used
in labeling new drug carrier systems.
This review tries to summarize the chemistry, preparation,
dosage, pharmacokinetics, precautions, quality control,
radiation dose and clinical and experimental applications
of Tc-99m-DTPA.
Keywords:
Tc-99m-DTPA, formulation, quality control, in vitro and
in vivo usage