History
 

FABAD  J. Pharm. Sci.
ISSN 1300-4182
Copyright Ó 2005 FABAD. All rights reserved 

FABAD J. Pharm. Sci., 20(4), 139-148, 1995.

Scientific Reviews

ABSTRACT

BUCCAL MUCOSA AS A ROUTE FOR DRUG DELIVERY

Sevda SENEL*,o, A.Atilla HINCAL*

*Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06100 Sihhiye, Ankara, TURKEY.
oCorresponding Author

Summary:
The structure and barrier properties of the buccal mucosa, which is an alternative route to gastrointestinal and parenteral routes in administration of metabolically unstable drugs, especially peptides and proteins, will be described here as well as th drug penetration and enhacement through this mucosa.

Key words:
Oral mucosa, Buccal mucosa, Buccal absorption, Penetration pathways, Barrier localization